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Cortisol
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Cortisol

The Cortisol/DHEA-S Ratio is a key indicator of your body's stress response and overall balance. Cortisol, a hormone produced in response to stress, and DHEA-S, a hormone that supports energy production and regeneration, are both vital for energy, metabolism, and longevity. By monitoring this ratio, you can gain valuable insights into how your body is coping with stress and whether you're optimising your performance and wellbeing. Testing this biomarker gives you a clearer understanding of your hormonal balance, empowering you to make proactive lifestyle changes for long-term health.

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What is the Cortisol/DHEA-S Ratio?

The Cortisol/DHEA-S ratio measures the balance between two hormones: cortisol, which helps manage stress, and DHEA-S, which is involved in energy and recovery. Tracking this ratio provides insights into how your body is adapting to stress and managing long-term energy levels.

Why does it matter for long-term health and wellbeing?

This ratio offers a clear view of how well your body manages stress and maintains energy. High cortisol levels, particularly when combined with low DHEA-S, can indicate that your body is not recovering effectively, which may impact your overall wellbeing. By keeping the ratio balanced, you support healthy energy metabolism and stress resilience.

What’s an optimal level of Cortisol/DHEA-S?

The optimal range for the Cortisol/DHEA-S ratio can vary, but generally, a balanced ratio suggests better energy regulation and recovery. It's important to track your personal baseline and adjust as needed for your health goals. The reference ranges from your lab will offer a guideline for interpreting your results.

What influences Cortisol/DHEA-S levels?

Factors like stress, sleep quality, diet, exercise, and lifestyle habits can all impact your cortisol and DHEA-S levels. Chronic stress, poor sleep, and inadequate nutrition can disrupt your hormonal balance, leading to imbalances in this ratio.

What does it mean if the Cortisol/DHEA-S ratio is outside the optimal range?

If the ratio is imbalanced, it may indicate that your body is experiencing heightened stress or insufficient recovery. This could lead to fatigue, difficulty managing stress, or lower energy levels over time. Regular monitoring can help you identify when adjustments to your lifestyle or habits are needed.

How can I support healthy Cortisol/DHEA-S levels?

To maintain a healthy ratio, focus on managing stress through mindfulness, exercise, and proper sleep. A balanced diet rich in antioxidants, vitamins, and minerals supports overall hormone production. Regular physical activity and a consistent sleep schedule can also help improve balance.

References

  1. Australian Institute of Health and Welfare. (2020). Hormonal health and wellbeing in Australia: Trends and statistics. AIHW.
  2. Zimmet, P.Z., Alberti, K.G.M., & Shaw, J. (2001). Global and societal implications of the diabetes epidemic. Nature, 414(6865), 782-787.
  3. Pereira, M. A., & Figueiredo, L. R. (2016). Impact of stress on health in adults: A review. Australian Journal of Psychology, 68(3), 179-188.

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Biological Age
1 marker

Biological age

A reflection of how your body is aging at the cellular level, linked to age risks and longevity.
Red Blood Cell (RBC) Count
Haemoglobin
Haematocrit
Mean Cell Volume (MCV)
Mean Cell Haemoglobin (MCH)
Mean Cell Haemoglobin Concentration (MCHC)
Red Cell Distribution Width (RDW)
Platelet Count
8 markers

Blood health

Key blood indicators like hemoglobin, inflammation, and oxygen transport for overall health.
Cholesterol Ratio
HDL Cholesterol
LDL Cholesterol
Non-HDL Cholesterol
Total Cholesterol
Triglycerides
6 markers

Heart health

Assesses cardiovascular health through cholesterol, lipids, and heart-related risk markers.
Cortisol
Dehydroepiandrosterone Sulfate (DHEA-S)
Free Thyroxine (T4)
Free Triiodothyronine (T3)
Thyroid stimulating hormone (TSH)
5 markers

Hormone balance

Evaluates hormone levels that impact energy, sleep, mood, and metabolism.
White Blood Cell (WBC) Count
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
6 markers

Immune system

Measures immune activity and inflammatory responses to assess body defenses.
High-Sensitivity C-Reactive Protein (hs-CRP)
1 marker

Inflammation status

Tracks signs of chronic or acute inflammation that may affect long-term disease risk.
Bicarbonate
Chloride
Creatinine
Potassium
Sodium
Urea
Uric acid
Anion Gap
Estimated Glomerular Filtration Rate (EGFR)
9 markers

Kidney function

Assesses kidney health through creatinine and other markers of blood filtration.
Alanine Aminotransferase
Albumin
Alkaline Phosphatase
Aspartate aminotransferase (AST)
Bilirubin
Gamma-glutamyl Transferase (GGT)
Globulin
Total Protein
8 markers

Liver health

Measures liver enzymes and proteins responsible for detoxification and metabolic health.
Fasting Glucose
Fasting Insulin
Haemoglobin A1c (HbA1c) IFCC mmol/m
Haemoglobin A1c (HbA1c) NGSP/DCCT %
HOMA-IR score
5 markers

Metabolic health

Evaluates energy processing with glucose, HbA1c, insulin, and related biomarkers.
Magnesium
1 marker

Vitamins & minerals

Analyzes essential nutrients that support immunity, energy, and overall wellbeing.
Creatine Kinase
1 marker

Muscle strength

Assesses biomarkers related to muscle performance, function, and recovery.
Biological Age
1 marker

Biological age

A reflection of how your body is aging at the cellular level, linked to age risks and longevity.
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