What is HS-CRP / HDL Ratio?
The HS-CRP / HDL ratio is the relationship between high-sensitivity C-reactive protein (HS-CRP), an indicator of inflammation, and HDL, the “good” cholesterol that helps remove fat from the bloodstream. This ratio provides a snapshot of inflammation levels relative to cholesterol health.
Why does it matter for long-term health and wellbeing?
The HS-CRP / HDL ratio is a useful indicator of inflammation and heart health, with a lower ratio reflecting better balance between inflammation and cardiovascular health. Tracking this ratio helps optimise overall wellness, energy, and metabolism over time.
What's an optimal level of HS-CRP / HDL Ratio?
Optimal Range:
- HS-CRP: Less than 1 mg/L for low inflammation
- HDL: Above 1.0 mmol/L for men and 1.3 mmol/L for women (An optimal ratio would show low CRP levels and high HDL, suggesting a healthier balance).
What influences HS-CRP / HDL levels?
Factors such as diet, physical activity, weight, and stress levels can impact these biomarkers. Regular exercise, a healthy diet, and stress management can support optimal levels.
What does it mean if HS-CRP / HDL is outside the optimal range?
A higher HS-CRP and a lower HDL may signal increased inflammation or suboptimal cardiovascular health, indicating areas where lifestyle improvements could be beneficial.
How can I support healthy HS-CRP / HDL levels?
To maintain healthy levels, focus on a balanced diet rich in antioxidants, omega-3 fatty acids, and healthy fats, regular physical activity, weight management, and stress reduction techniques like mindfulness or relaxation exercises.
References
- Silventoinen, K., Sammalisto, S., Perola, M., et al. (2003). Heritability of adult body height: a comparative study of twin cohorts in eight countries. Twin Research, 6(5), 399-408.
- Perkins, J.M., Subramanian, S.V., Davey Smith, G., & Özaltin, E. (2016). Adult height, nutrition, and population health. Nutrition Reviews, 74(3), 149-165.
- Silventoinen, K., Kaprio, J., Lahelma, E., et al. (2016). Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts. Scientific Reports, 6, 28496.
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