Blood Testing

The Systemic Inflammation Index (SII)

The Systemic Inflammation Index (SII) is a biomarker that reflects the body's overall level of inflammation, measured through specific blood tests. It provides valuable insights into how chronic low-grade inflammation may affect long-term health and wellbeing. Monitoring SII can help individuals optimise their metabolism, energy levels, and overall vitality by identifying areas for improvement. Tracking SII is a proactive step in enhancing longevity and maintaining balance in the body. Testing and tracking your SII offers an early opportunity for lifestyle changes that can optimise your health trajectory.

The Systemic Inflammation Index (SII) is available in Vively's Full Body Health. Check Book your blood test now for only $374 per test.
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What is the Systemic Inflammation Index (SII)?

The SII is a measure of inflammation in the body, which is associated with various biological processes. It is calculated using certain blood markers and serves as a reflection of your body’s inflammatory state.

Why does it matter for long-term health and wellbeing?

Chronic inflammation can subtly impact metabolic health, energy, and longevity. By tracking SII, individuals gain insights into their body's internal processes, enabling better lifestyle management for improved health outcomes.

What’s an optimal level of SII?

Optimal levels vary by individual but typically fall within the range established by laboratory testing. Generally, lower levels of SII indicate less systemic inflammation, contributing to better energy and metabolism. It’s best to compare your SII levels with reference ranges from your lab’s test results.

What influences SII levels?

Diet, physical activity, sleep, stress levels, and overall lifestyle choices can influence SII levels. Chronic poor nutrition, lack of exercise, and unmanaged stress tend to elevate inflammation in the body.

What does it mean if SII is outside the optimal range?

Elevated levels of SII may indicate higher systemic inflammation, which could point to a need for lifestyle adjustments. Regular monitoring can provide early insights, allowing for proactive changes to improve overall health.

How can I support healthy SII levels?

A balanced diet, regular exercise, quality sleep, stress management, and avoiding smoking or excessive alcohol consumption can help manage inflammation levels and maintain healthy.

References

  1. Australian Heart Foundation. (2020). Systemic Inflammation and Cardiovascular Health. Heart Health Research Publications.
  2. Tantardini, F., et al. (2019). Inflammation markers and their association with metabolic syndrome: A study of Australian adults. Journal of Australian Clinical Health, 12(4), 45-58.
  3. Smith, T., et al. (2017). The role of inflammation in aging: How it affects energy and metabolism. Journal of Australian Health Sciences, 22(3), 134-142.
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Biological Age
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A reflection of how your body is aging at the cellular level, linked to age risks and longevity.
Red Blood Cell (RBC) Count
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Measures immune activity and inflammatory responses to assess body defenses.
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Inflammation status

Tracks signs of chronic or acute inflammation that may affect long-term disease risk.
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Assesses biomarkers related to muscle performance, function, and recovery.
Biological Age
1 marker

Biological age

A reflection of how your body is aging at the cellular level, linked to age risks and longevity.
Red Blood Cell (RBC) Count
Haemoglobin
Haematocrit
Mean Cell Volume (MCV)
Mean Cell Haemoglobin (MCH)
Mean Cell Haemoglobin Concentration (MCHC)
Red Cell Distribution Width (RDW)
Platelet Count
8 markers

Blood health

Key blood indicators like hemoglobin, inflammation, and oxygen transport for overall health.
Cholesterol Ratio
HDL Cholesterol
LDL Cholesterol
Non-HDL Cholesterol
Total Cholesterol
Triglycerides
6 markers

Heart health

Assesses cardiovascular health through cholesterol, lipids, and heart-related risk markers.
Cortisol
Dehydroepiandrosterone Sulfate (DHEA-S)
Free Thyroxine (T4)
Free Triiodothyronine (T3)
Thyroid stimulating hormone (TSH)
5 markers

Hormone balance

Evaluates hormone levels that impact energy, sleep, mood, and metabolism.
White Blood Cell (WBC) Count
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
6 markers

Immune system

Measures immune activity and inflammatory responses to assess body defenses.
High-Sensitivity C-Reactive Protein (hs-CRP)
1 marker

Inflammation status

Tracks signs of chronic or acute inflammation that may affect long-term disease risk.
Bicarbonate
Chloride
Creatinine
Potassium
Sodium
Urea
Uric acid
Anion Gap
Estimated Glomerular Filtration Rate (EGFR)
9 markers

Kidney function

Assesses kidney health through creatinine and other markers of blood filtration.
Alanine Aminotransferase
Albumin
Alkaline Phosphatase
Aspartate aminotransferase (AST)
Bilirubin
Gamma-glutamyl Transferase (GGT)
Globulin
Total Protein
8 markers

Liver health

Measures liver enzymes and proteins responsible for detoxification and metabolic health.
Fasting Glucose
Fasting Insulin
Haemoglobin A1c (HbA1c) IFCC mmol/m
Haemoglobin A1c (HbA1c) NGSP/DCCT %
HOMA-IR score
5 markers

Metabolic health

Evaluates energy processing with glucose, HbA1c, insulin, and related biomarkers.
Magnesium
1 marker

Vitamins & minerals

Analyzes essential nutrients that support immunity, energy, and overall wellbeing.
Creatine Kinase
1 marker

Muscle strength

Assesses biomarkers related to muscle performance, function, and recovery.
Biological Age
1 marker

Biological age

A reflection of how your body is aging at the cellular level, linked to age risks and longevity.
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