What is Triglyceride / HDL Cholesterol (Molar Ratio)?
This ratio is calculated by dividing your fasting triglyceride concentration by your HDL-cholesterol concentration (both in the same unit, usually mmol/L in Australia). It expresses the relationship between the fat your body is storing or transporting (triglycerides) and the cholesterol-clearing lipoprotein (HDL-C) working in reverse cholesterol transport. Because triglycerides and HDL-C move in opposite directions when metabolic stress increases, the ratio becomes a useful marker of how well your metabolic-lipid system is functioning.
Why does it matter for long-term health and wellbeing?
While the individual levels of triglycerides or HDL-C are informative, the ratio gives a clearer picture of underlying lipid transport-metabolism dynamics and how they tie into key long-term health performance variables. Elevated Tg/HDL ratios have been shown to correlate with features of central fat accumulation, insulin-resistance patterns and metabolic dysfunction — all of which influence how well your body maintains cellular energy, recovers from stress, and sustains vascular/metabolic resilience.
In other words, by observing this ratio you gain an early signal of sub-optimal lipid-metabolic handling, allowing you to optimise now (for energy, recovery, and clarity) rather than waiting for later consequences.
What’s an optimal level of Triglyceride / HDL Cholesterol (Molar Ratio)?
- Reference (lab) ranges: for men: less than 3.0; for women: less than 2.2.
- Optimal (performance-oriented) range: for men: less than 2.6; for women: less than 1.7.
These figures reflect Australian measurement units (mmol/L) and aim to support proactive wellbeing rather than disease thresholds.
Note: Exact cut-offs may vary by ethnicity and individual profile.
What influences my Triglyceride / HDL Cholesterol ratio?
Many modifiable lifestyle factors influence this ratio:
- Body composition and central (abdominal) fat accumulation — more central fat tends to raise triglycerides and reduce HDL.
- Insulin sensitivity/metabolic health — when insulin resistance increases, triglycerides often rise and HDL falls.
- Dietary intake (especially excess kilojoules/energy, refined carbohydrates, saturated/added sugars) increases triglycerides.
- Physical activity and cardiovascular fitness — higher activity tends to improve HDL-C and reduce triglycerides.
- Alcohol intake, smoking, sleep quality and stress levels also influence both triglycerides and HDL-C.
- Genetic or ethnic factors—some populations may naturally have different lipid handling, and so ratio cut-offs may differ.
What does it mean if the ratio is outside the optimal range?
If your Tg/HDL ratio is above the optimal range, it suggests your metabolic-lipid handling may not be at its peak. That doesn’t mean something is “wrong” — rather, it means you’ve identified a useful insight: your lipid transport and metabolism network is under more strain than ideal. For proactive health and performance, this is your opportunity to adjust lifestyle, nutrition, fitness and recovery to shift the ratio downward (towards the optimal range). If the ratio is within the optimal range, that is a positive sign — it suggests your current lifestyle is supporting efficient lipid-cholesterol transport and metabolic resilience.
How can I support healthy Triglyceride / HDL Cholesterol levels and ratio?
- Maintain a healthy body composition and minimise central fat accumulation through movement and effective strength/cardiovascular training.
- Focus on dietary patterns that reduce excess energy intake, minimise added/refined sugars, balance healthy fats (emphasising mono- and poly-unsaturated fats) and include plenty of fibre-rich whole foods.
- Promote regular aerobic and resistance exercise (which tends to raise HDL and lower triglycerides).
- Moderate alcohol intake, avoiding smoking, optimising sleep and managing stress — each of these influences lipid metabolism.
- Align with recovery and activity-cycle practices so your metabolic system is supported (for example, avoiding prolonged sedentary periods, ensuring movement breaks, optimising post-exercise nutrition).
- Track regularly: since the ratio can move relatively rapidly in response to lifestyle change, you can monitor progress (for example every 3-6 months) and use that feedback to refine your plan.
This information is provided for general health and wellness purposes only and does not replace medical advice.
References
- Kosmas, C.E., et al. (2023). The Triglyceride/High-Density Lipoprotein Cholesterol (TG/HDL-C) Ratio: A • biomarker linking lipid transport and metabolic risk.
- Guan, C.–L., Liu, H.–T., Chen, D.–H., et al. (2022). Is an elevated triglyceride/high-density lipoprotein cholesterol ratio associated with poor prognosis of coronary heart disease? Medicine, 101(45):e31123.
- CSIRO. (2022). Cholesterol facts. CSIRO Health & Medical Research.