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TyG Index
Blood Testing

TyG Index

TyG Index (Triglyceride-Glucose Index) is a calculated marker from fasting triglycerides and fasting glucose, reported within a metabolic and cardiometabolic risk panel. Higher TyG Index values suggest reduced insulin sensitivity and may be seen with insulin resistance, metabolic syndrome, non-alcoholic fatty liver disease, and dyslipidaemia (high triglycerides, low HDL-C), while lower values generally indicate more efficient glucose–lipid handling. This matters because early insulin resistance can affect energy regulation, weight gain risk, triglycerides, and cardiovascular health before HbA1c shifts. A TyG Index blood test result is best interpreted alongside fasting insulin, HbA1c, HDL-C, LDL-C, waist measures and liver enzymes (ALT/AST) to clarify drivers.

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What is the TyG index?

The TyG index (Triglyceride-Glucose index) is a calculated measure that combines fasting triglyceride and glucose levels to estimate how efficiently your body utilises insulin and processes energy. It provides a snapshot of overall metabolic health.

Why does it matter for long-term health and wellbeing?

Your TyG index reflects how well your body balances glucose and fat metabolism. Maintaining a healthy level supports consistent energy, efficient fuel use, and optimal cellular performance—all key factors for longevity and overall wellness.

What’s an optimal level of TyG index?

  • Optimal range: <8.44
  • Reference range: <8.82 (men), <8.73 (women)

Values within the optimal range indicate balanced glucose and lipid metabolism.

What influences TyG index levels?

TyG index levels can shift based on dietary patterns, physical activity, sleep quality, stress levels, and body composition. Diets high in refined carbohydrates or saturated fats, or inconsistent exercise habits, can raise the index over time.

What does it mean if TyG index is outside the optimal range?

A higher TyG index suggests that your body may be less efficient at managing glucose and lipids, which can impact your energy levels and metabolic efficiency. Tracking and adjusting your habits can help bring the index back within an optimal range.

How can I support healthy TyG index levels?

Focusing on balanced meals rich in whole foods, fibre, and unsaturated fats, along with regular movement, restorative sleep, and stress management, can all help maintain a healthy TyG index. Monitoring your progress through regular blood tests provides clear feedback on your lifestyle’s impact.

This information is provided for general health and wellness purposes only and does not replace medical advice.

References

  1. Australian Institute of Health and Welfare. (2024). Heart, stroke and vascular disease: Australian facts (Cat. no. CVD 92). Canberra: AIHW.
  2. The Royal College of Pathologists of Australasia. (2009). RCPA Manual (5th ed.). Sydney: RCPA.
  3. Simental-Mendía, L. E., Rodríguez-Morán, M., & Guerrero-Romero, F. (2008). The product of fasting glucose and triglycerides as a surrogate for identifying insulin resistance. Metabolic Syndrome and Related Disorders, 6(4), 299-304.
  4. Guerrero-Romero, F., & Simental-Mendía, L. E. (2010). The triglyceride and glucose index: a simple measure of insulin sensitivity. Journal of Clinical Endocrinology & Metabolism, 95(7), 3347-3351.
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Biological age

A reflection of how your body is aging at the cellular level, linked to age risks and longevity.
Red Blood Cell (RBC) Count
Haemoglobin
Haematocrit
Mean Cell Volume (MCV)
Mean Cell Haemoglobin (MCH)
Mean Cell Haemoglobin Concentration (MCHC)
Red Cell Distribution Width (RDW)
Platelet Count
8 markers

Blood health

Key blood indicators like hemoglobin, inflammation, and oxygen transport for overall health.
Cholesterol Ratio
HDL Cholesterol
LDL Cholesterol
Non-HDL Cholesterol
Total Cholesterol
Triglycerides
6 markers

Heart health

Assesses cardiovascular health through cholesterol, lipids, and heart-related risk markers.
Cortisol
Dehydroepiandrosterone Sulfate (DHEA-S)
Free Thyroxine (T4)
Free Triiodothyronine (T3)
Thyroid stimulating hormone (TSH)
5 markers

Hormone balance

Evaluates hormone levels that impact energy, sleep, mood, and metabolism.
White Blood Cell (WBC) Count
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
6 markers

Immune system

Measures immune activity and inflammatory responses to assess body defenses.
High-Sensitivity C-Reactive Protein (hs-CRP)
1 marker

Inflammation status

Tracks signs of chronic or acute inflammation that may affect long-term disease risk.
Bicarbonate
Chloride
Creatinine
Potassium
Sodium
Urea
Uric acid
Anion Gap
Estimated Glomerular Filtration Rate (EGFR)
9 markers

Kidney function

Assesses kidney health through creatinine and other markers of blood filtration.
Alanine Aminotransferase
Albumin
Alkaline Phosphatase
Aspartate aminotransferase (AST)
Bilirubin
Gamma-glutamyl Transferase (GGT)
Globulin
Total Protein
8 markers

Liver health

Measures liver enzymes and proteins responsible for detoxification and metabolic health.
Fasting Glucose
Fasting Insulin
Haemoglobin A1c (HbA1c) IFCC mmol/m
Haemoglobin A1c (HbA1c) NGSP/DCCT %
HOMA-IR score
5 markers

Metabolic health

Evaluates energy processing with glucose, HbA1c, insulin, and related biomarkers.
Magnesium
1 marker

Vitamins & minerals

Analyzes essential nutrients that support immunity, energy, and overall wellbeing.
Creatine Kinase
1 marker

Muscle strength

Assesses biomarkers related to muscle performance, function, and recovery.
Biological Age
1 marker

Biological age

A reflection of how your body is aging at the cellular level, linked to age risks and longevity.
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